Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus | |
ATP | - |
Saccharomyces cerevisiae | |
ATP | - |
Enterobacteria phage T6 | |
ATP | - |
Tequintavirus T5 | |
ATP | stimulation of UDP reduction | Escherichia coli | |
ATP | stimulation of UDP reduction | Homo sapiens | |
ATP | stimulation of UDP reduction | Bos taurus | |
ATP | stimulation of UDP reduction | Oryctolagus cuniculus | |
ATP | stimulation of UDP reduction | Tequatrovirus T4 | |
ATP | stimulation of CDP reduction | Tetradesmus obliquus | |
ATP | stimulation of CDP reduction | Escherichia coli | |
ATP | stimulation of CDP reduction | Homo sapiens | |
ATP | stimulation of CDP reduction | Rattus norvegicus | |
ATP | stimulation of CDP reduction | Bos taurus | |
ATP | stimulation of CDP reduction | Oryctolagus cuniculus | |
ATP | stimulation of CDP reduction | Mesocricetus auratus | |
ATP | stimulation of CDP reduction | Tequatrovirus T4 | |
dCTP | - |
Mesocricetus auratus | |
dCTP | stimulation of UDP reduction | Tetradesmus obliquus | |
dCTP | stimulation of UDP reduction | Mus musculus | |
dCTP | stimulation of UDP reduction | Escherichia coli | |
dCTP | stimulation of UDP reduction | Homo sapiens | |
dCTP | stimulation of UDP reduction | Rattus norvegicus | |
dCTP | stimulation of UDP reduction | Saccharomyces cerevisiae | |
dCTP | stimulation of UDP reduction | Bos taurus | |
dCTP | stimulation of UDP reduction | Oryctolagus cuniculus | |
dCTP | stimulation of UDP reduction | Tequatrovirus T4 | |
dGTP | - |
Mesocricetus auratus | |
dGTP | - |
Enterobacteria phage T6 | |
dGTP | - |
Tequintavirus T5 | |
dGTP | stimulation of ADP reduction | Escherichia coli | |
dGTP | stimulation of ADP reduction | Homo sapiens | |
dGTP | stimulation of ADP reduction | Bos taurus | |
dGTP | stimulation of ADP reduction | Oryctolagus cuniculus | |
dGTP | stimulation of tubercidin diphosphate reduction | Tetradesmus obliquus | |
dGTP | stimulation of tubercidin diphosphate reduction | Mus musculus | |
dGTP | stimulation of tubercidin diphosphate reduction | Escherichia coli | |
dGTP | stimulation of tubercidin diphosphate reduction | Homo sapiens | |
dGTP | stimulation of tubercidin diphosphate reduction | Rattus norvegicus | |
dGTP | stimulation of tubercidin diphosphate reduction | Saccharomyces cerevisiae | |
dGTP | stimulation of tubercidin diphosphate reduction | Bos taurus | |
dGTP | stimulation of tubercidin diphosphate reduction | Oryctolagus cuniculus | |
dGTP | stimulation of tubercidin diphosphate reduction | Tequatrovirus T4 | |
dTTP | - |
Enterobacteria phage T6 | |
dTTP | - |
Tequintavirus T5 | |
dTTP | stimulation of UDP reduction | Tetradesmus obliquus | |
dTTP | stimulation of UDP reduction | Mus musculus | |
dTTP | stimulation of UDP reduction | Escherichia coli | |
dTTP | stimulation of UDP reduction | Homo sapiens | |
dTTP | stimulation of UDP reduction | Rattus norvegicus | |
dTTP | stimulation of UDP reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of UDP reduction | Bos taurus | |
dTTP | stimulation of UDP reduction | Oryctolagus cuniculus | |
dTTP | stimulation of UDP reduction | Tequatrovirus T4 | |
dTTP | stimulation of CDP reduction | Tetradesmus obliquus | |
dTTP | stimulation of CDP reduction | Mus musculus | |
dTTP | stimulation of CDP reduction | Escherichia coli | |
dTTP | stimulation of CDP reduction | Homo sapiens | |
dTTP | stimulation of CDP reduction | Rattus norvegicus | |
dTTP | stimulation of CDP reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of CDP reduction | Bos taurus | |
dTTP | stimulation of CDP reduction | Oryctolagus cuniculus | |
dTTP | stimulation of CDP reduction | Tequatrovirus T4 | |
dTTP | stimulation of GDP reduction | Mus musculus | |
dTTP | stimulation of GDP reduction | Escherichia coli | |
dTTP | stimulation of GDP reduction | Homo sapiens | |
dTTP | stimulation of GDP reduction | Rattus norvegicus | |
dTTP | stimulation of GDP reduction | Bos taurus | |
dTTP | stimulation of GDP reduction | Oryctolagus cuniculus | |
dTTP | stimulation of GDP reduction | Tequatrovirus T4 | |
dTTP | stimulation of purine riboside diphosphate reduction | Tetradesmus obliquus | |
dTTP | stimulation of purine riboside diphosphate reduction | Mus musculus | |
dTTP | stimulation of purine riboside diphosphate reduction | Escherichia coli | |
dTTP | stimulation of purine riboside diphosphate reduction | Homo sapiens | |
dTTP | stimulation of purine riboside diphosphate reduction | Rattus norvegicus | |
dTTP | stimulation of purine riboside diphosphate reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of purine riboside diphosphate reduction | Bos taurus | |
dTTP | stimulation of purine riboside diphosphate reduction | Oryctolagus cuniculus | |
dTTP | stimulation of purine riboside diphosphate reduction | Tequatrovirus T4 | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Tetradesmus obliquus | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Mus musculus | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Escherichia coli | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Homo sapiens | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Rattus norvegicus | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Bos taurus | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Oryctolagus cuniculus | |
dTTP | stimulation of 2,6-diaminopurine riboside reduction | Tequatrovirus T4 | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Tetradesmus obliquus | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Mus musculus | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Escherichia coli | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Homo sapiens | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Rattus norvegicus | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Bos taurus | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Oryctolagus cuniculus | |
dTTP | stimulation of 2-aminopurineriboside diphosphate reduction | Tequatrovirus T4 | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Tetradesmus obliquus | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Mus musculus | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Escherichia coli | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Homo sapiens | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Rattus norvegicus | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Saccharomyces cerevisiae | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Bos taurus | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Oryctolagus cuniculus | |
dTTP | stimulation of benzimidazoleriboside diphosphate reduction | Tequatrovirus T4 | |
additional information | overview: stimulation of various enzymes | Tetradesmus obliquus | |
additional information | overview: stimulation of various enzymes | Mus musculus | |
additional information | overview: stimulation of various enzymes | Escherichia coli | |
additional information | overview: stimulation of various enzymes | Homo sapiens | |
additional information | overview: stimulation of various enzymes | Rattus norvegicus | |
additional information | overview: stimulation of various enzymes | Saccharomyces cerevisiae | |
additional information | overview: stimulation of various enzymes | Bos taurus | |
additional information | overview: stimulation of various enzymes | Oryctolagus cuniculus | |
additional information | overview: stimulation of various enzymes | Tequatrovirus T4 | |
additional information | stimulation by effector nucleotides | Tetradesmus obliquus | |
additional information | stimulation by effector nucleotides | Mus musculus | |
additional information | stimulation by effector nucleotides | Escherichia coli | |
additional information | stimulation by effector nucleotides | Homo sapiens | |
additional information | stimulation by effector nucleotides | Rattus norvegicus | |
additional information | stimulation by effector nucleotides | Saccharomyces cerevisiae | |
additional information | stimulation by effector nucleotides | Bos taurus | |
additional information | stimulation by effector nucleotides | Oryctolagus cuniculus | |
additional information | stimulation by effector nucleotides | Tequatrovirus T4 | |
additional information | stimulation with various substrates | Tetradesmus obliquus | |
additional information | stimulation with various substrates | Mus musculus | |
additional information | stimulation with various substrates | Escherichia coli | |
additional information | stimulation with various substrates | Homo sapiens | |
additional information | stimulation with various substrates | Rattus norvegicus | |
additional information | stimulation with various substrates | Saccharomyces cerevisiae | |
additional information | stimulation with various substrates | Bos taurus | |
additional information | stimulation with various substrates | Oryctolagus cuniculus | |
additional information | stimulation with various substrates | Tequatrovirus T4 |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Bos taurus | |
1,10-phenanthroline | - |
Escherichia coli | |
1,10-phenanthroline | - |
Homo sapiens | |
1,10-phenanthroline | - |
Mus musculus | |
1,10-phenanthroline | - |
Oryctolagus cuniculus | |
1,10-phenanthroline | - |
Rattus norvegicus | |
1,10-phenanthroline | - |
Saccharomyces cerevisiae | |
1,10-phenanthroline | - |
Tequatrovirus T4 | |
1,10-phenanthroline | - |
Tetradesmus obliquus | |
2,3-Dihydro-1H-pyrazolo[2,3-a]imidazole | - |
Mus musculus | |
2-Nitro-imidazole | trivial name azomycin | Escherichia coli | |
3,5-diamino-1H-1,2,4-triazole | trivial name guanazole | Bos taurus | |
3,5-diamino-1H-1,2,4-triazole | trivial name guanazole | Homo sapiens | |
3,5-diamino-1H-1,2,4-triazole | trivial name guanazole | Mesocricetus auratus | |
3,5-diamino-1H-1,2,4-triazole | trivial name guanazole | Mus musculus | |
3-Methyl-4-nitrophenol | - |
Mesocricetus auratus | |
4-Amino-2-phenylimidazole-5-carboxamide | - |
Rattus norvegicus | |
4-Methyl-5-amino isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Escherichia coli | |
4-Methyl-5-amino isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Mus musculus | |
4-Methyl-5-amino isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Rattus norvegicus | |
5-(1-Aziridinyl)-2,4-dinitrobenzamide | - |
Homo sapiens | |
5-(1-Aziridinyl)-2,4-dinitrobenzamide | - |
Rattus norvegicus | |
8-hydroxyquinoline | - |
Escherichia coli | |
8-hydroxyquinoline | - |
Oryctolagus cuniculus | |
8-hydroxyquinoline | - |
Rattus norvegicus | |
8-hydroxyquinoline 5-sulfonate | - |
Escherichia coli | |
8-hydroxyquinoline 5-sulfonate | - |
Oryctolagus cuniculus | |
8-hydroxyquinoline 5-sulfonate | - |
Rattus norvegicus | |
Acetohydroxamic acid | - |
Escherichia coli | |
aurintricarboxylate | oligomeric form | Escherichia coli | |
aurintricarboxylate | oligomeric form | Saccharomyces cerevisiae | |
aurintricarboxylate | oligomeric form | Tetradesmus obliquus | |
bathophenanthroline disulfonate | - |
Bos taurus | |
bathophenanthroline disulfonate | - |
Mus musculus | |
bathophenanthroline disulfonate | - |
Oryctolagus cuniculus | |
Catechol derivatives | - |
Rattus norvegicus | |
Cibacron blue F3 GA | - |
Mus musculus | |
desferrioxamine | - |
Homo sapiens | |
EDTA | - |
Bos taurus | |
EDTA | - |
Escherichia coli | |
EDTA | - |
Homo sapiens | |
EDTA | - |
Mesocricetus auratus | |
EDTA | - |
Mus musculus | |
EDTA | - |
Rattus norvegicus | |
EDTA | - |
Tetradesmus obliquus | |
ethyleneglycol-bis-(2-aminoethylether)-N,N,N',N'-tetraacetic acid | trivial name EGTA | Mus musculus | |
Fe2+ | - |
Rattus norvegicus | |
Fe2+ | concentrations higher than 0.1-1 mM | Tetradesmus obliquus | |
glutathione | analogs with aromatic substituents | Mus musculus | |
Hydroxyurea | 1 mM, complete inactivation of thymus enzyme | Bos taurus | |
Hydroxyurea | - |
Escherichia coli | |
Hydroxyurea | - |
Homo sapiens | |
Hydroxyurea | - |
Mesocricetus auratus | |
Hydroxyurea | - |
Mus musculus | |
Hydroxyurea | - |
Oryctolagus cuniculus | |
Hydroxyurea | - |
Rattus norvegicus | |
Hydroxyurea | - |
Saccharomyces cerevisiae | |
Hydroxyurea | - |
Tequatrovirus T4 | |
Hydroxyurea | - |
Tequintavirus T5 | |
Hydroxyurea | - |
Tetradesmus obliquus | |
Isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Bos taurus | |
Isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Homo sapiens | |
Isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Mus musculus | |
Isoquinoline-1-carboxaldehyde thiosemicarbazone | - |
Rattus norvegicus | |
meso-alpha,beta-Diphenylsuccinate | - |
Mus musculus | |
Mn2+ | concentrations higher than 0.1-1 mM | Tetradesmus obliquus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Bos taurus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Escherichia coli | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Homo sapiens | |
additional information | - |
Mesocricetus auratus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Mus musculus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Oryctolagus cuniculus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Rattus norvegicus | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Saccharomyces cerevisiae | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Tequatrovirus T4 | |
additional information | overview: naturally occuring inhibitors e.g. proteins and nucleotides | Tetradesmus obliquus | |
n-Hexanohydroxamic acid | - |
Escherichia coli | |
N-Methylhydroxylamine | - |
Escherichia coli | |
Pyridine-2-carboxaldehyde thiosemicarbazone | - |
Escherichia coli | |
Pyridine-2-carboxaldehyde thiosemicarbazone | - |
Homo sapiens | |
Pyridine-2-carboxaldehyde thiosemicarbazone | - |
Mus musculus | |
Pyridine-2-carboxaldehyde thiosemicarbazone | - |
Rattus norvegicus | |
pyridoxal 5'-phosphate/NaBH4 | - |
Mus musculus | |
Pyrogallol derivatives | - |
Rattus norvegicus | |
Thenoyltrifluoroacetone | - |
Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | - |
Tetradesmus obliquus | |
Iron | - |
Mus musculus | |
Iron | - |
Rattus norvegicus | |
Iron | - |
Bos taurus | |
Iron | - |
Oryctolagus cuniculus | |
Iron | - |
Tequatrovirus T4 | |
Iron | subunit B2 contains iron, nonheme-like porphyrin complexes | Escherichia coli | |
Mg2+ | - |
Oryctolagus cuniculus | |
Mg2+ | - |
Mesocricetus auratus | |
Mg2+ | - |
Tequatrovirus T4 | |
Mg2+ | 2fold stimulation | Bos taurus | |
Mg2+ | subunit B1 requires Mg2+ ions in the 10 mM concentration range for activity | Escherichia coli | |
additional information | - |
Mus musculus | |
additional information | Mg2+ is not required for activity in vitro | Tetradesmus obliquus | |
additional information | Mg2+ is not required for activity in vitro | Rattus norvegicus | |
additional information | Mg2+ is not required for activity in vitro | Saccharomyces cerevisiae | |
additional information | Mg2+ is not required for activity in vitro | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
alpha2beta2, 2 * 85000 + 2 * 35000, enzyme induced in Escherichia coli after infection with bacteriophage T4, SDS-PAGE | Tequatrovirus T4 |
39000 | - |
alpha, alpha,beta2, 2 * 80000 + 2 * 39000, SDS-PAGE | Escherichia coli |
45000 | - |
4 * 45000 + 1 * 45000 + 1 * 75000, regenerating liver | Rattus norvegicus |
55000 | - |
2 * 84000 + 2 * 55000, SDS-PAGE | Bos taurus |
75000 | - |
4 * 45000 + 1 * 45000 + 1 * 75000, regenerating liver | Rattus norvegicus |
75000 | - |
2 * 90000 + x * 75000, most likely 1 75000 Da subunit, SDS-PAGE | Tetradesmus obliquus |
78000 | - |
alpha,alphabeta2, 2 * 82000 + 2 * 78000, each subunit composed of 2 polypeptide chains, subunit B1, 82000 Da, sedimentation equilibrium centrifugation, subunit B2, low speed sedimentation equilibrium centrifugation | Escherichia coli |
80000 | - |
alpha, alpha,beta2, 2 * 80000 + 2 * 39000, SDS-PAGE | Escherichia coli |
82000 | - |
alpha,alphabeta2, 2 * 82000 + 2 * 78000, each subunit composed of 2 polypeptide chains, subunit B1, 82000 Da, sedimentation equilibrium centrifugation, subunit B2, low speed sedimentation equilibrium centrifugation | Escherichia coli |
84000 | - |
2 * 84000 + 2 * 55000, SDS-PAGE | Bos taurus |
85000 | - |
alpha2beta2, 2 * 85000 + 2 * 35000, enzyme induced in Escherichia coli after infection with bacteriophage T4, SDS-PAGE | Tequatrovirus T4 |
90000 | - |
2 * 90000 + x * 75000, most likely 1 75000 Da subunit, SDS-PAGE | Tetradesmus obliquus |
90000 | - |
2 * 90000 + x * ?, Novikoff hepatoma cells | Escherichia coli |
100000 | - |
alpha,beta, 1 * 100000 + 1 * 100000, Molt F4 lymphoblast cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside diphosphate + reduced thioredoxin | Tetradesmus obliquus | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Mus musculus | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Escherichia coli | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Homo sapiens | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Rattus norvegicus | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Saccharomyces cerevisiae | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Bos taurus | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Oryctolagus cuniculus | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Tequatrovirus T4 | enzyme catalyzes the first unique step in DNA synthesis | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Enterobacteria phage T6 | - |
- |
- |
Escherichia coli | - |
- |
- |
Homo sapiens | - |
Molt 4F cells | - |
Mesocricetus auratus | - |
- |
- |
Mus musculus | - |
Ehrlich ascites tumor cells | - |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
Novikoff hepatoma cells | - |
Saccharomyces cerevisiae | - |
- |
- |
Tequatrovirus T4 | - |
- |
- |
Tequintavirus T5 | - |
- |
- |
Tetradesmus obliquus | - |
green algae | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Tetradesmus obliquus | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Mus musculus | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Escherichia coli | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Homo sapiens | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Rattus norvegicus | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Saccharomyces cerevisiae | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Bos taurus | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Oryctolagus cuniculus | |
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Tequatrovirus T4 |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Oryctolagus cuniculus | - |
Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
liver | regenerating liver | Rattus norvegicus | - |
lymphoblast | Molt 4F cells | Homo sapiens | - |
Novikoff ascites tumor cell | - |
Rattus norvegicus | - |
thymus | calf | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,6-diaminopurineriboside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxy-2,6-diaminopurineriboside diphosphate + H2O | - |
? | |
2-aminopurineriboside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxy-2-aminopurineriboside diphosphate + H2O | - |
? | |
benzimidazoleriboside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxybenzimidazolriboside diphosphate + H2O | - |
? | |
purineriboside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxypurineriboside diphosphate + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Tetradesmus obliquus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Mus musculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Homo sapiens | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Saccharomyces cerevisiae | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Bos taurus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Oryctolagus cuniculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Mesocricetus auratus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Tequatrovirus T4 | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Enterobacteria phage T6 | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Tequintavirus T5 | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Tetradesmus obliquus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Mus musculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Escherichia coli | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Homo sapiens | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Saccharomyces cerevisiae | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Bos taurus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Oryctolagus cuniculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | enzyme catalyzes the first unique step in DNA synthesis | Tequatrovirus T4 | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
tubercidin diphosphate + reduced thioredoxin | 14% of GDP reduction rate | Escherichia coli | 2'-deoxytubercidin diphosphate + oxidized thioredoxin + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | - |
Rattus norvegicus |
? | - |
Bos taurus |
? | 2 * 90000 + x * 75000, most likely 1 75000 Da subunit, SDS-PAGE | Tetradesmus obliquus |
? | 2 * 90000 + x * ?, Novikoff hepatoma cells | Escherichia coli |
dimer | alpha,beta, 1 * 100000 + 1 * 100000, Molt F4 lymphoblast cells | Homo sapiens |
hexamer | 4 * 45000 + 1 * 45000 + 1 * 75000, regenerating liver | Rattus norvegicus |
tetramer | alpha2beta2, 2 * 85000 + 2 * 35000, enzyme induced in Escherichia coli after infection with bacteriophage T4, SDS-PAGE | Tequatrovirus T4 |
tetramer | alpha,alpha'beta2, 2 * 82000 + 2 * 78000, each subunit composed of 2 polypeptide chains, subunit B1, 82000 Da, sedimentation equilibrium centrifugation, subunit B2, low speed sedimentation equilibrium centrifugation | Escherichia coli |
tetramer | 2 * 84000 + 2 * 55000, SDS-PAGE | Bos taurus |
tetramer | alpha, alpha',beta2, 2 * 80000 + 2 * 39000, SDS-PAGE | Escherichia coli |